What is a Certificate of Analysis?
A Certificate of Analysis (COA) is a technical document that reports the analytical testing results for a specific production batch. COAs provide objective data on product identity, purity, and quality parameters determined through validated laboratory methods.
COA Components
Product Information
Product name, catalog number, and batch/lot number uniquely identifying the specific production run.
Analysis Date
Date when analytical testing was performed, establishing the timeframe of quality verification.
Test Methods
Analytical techniques employed for quality assessment, such as HPLC, mass spectrometry, or amino acid analysis.
Specifications
Acceptance criteria defining the quality standards each parameter must meet.
Results
Actual measured values obtained from analytical testing, reported alongside specifications for comparison.
Conformance Status
Indication of whether results meet specification requirements.
Batch Specificity
COAs are batch-specific documents. The analytical results reported apply exclusively to the production lot referenced by the batch number. Different batches of the same product may have slightly different analytical values, all within specification limits.
When referencing COA data in research documentation, the batch number should be cited to maintain traceability.
Interpreting Results
Purity
HPLC purity represents the percentage of the target compound relative to total detected peaks. A purity of 99.1% indicates that 99.1% of detected material is the target peptide, with 0.9% representing related impurities or byproducts.
Molecular Mass
Mass spectrometry results confirm peptide identity by comparing observed mass to theoretical mass. Agreement within the specified tolerance confirms molecular identity.
Peptide Content
Peptide content represents the mass fraction of actual peptide in the lyophilized product. The remainder consists of counterions, water, and residual solvents. This value is used for accurate weight-based concentration calculations.
Using COA Data
COA data supports research quality in several ways:
- Verification that materials meet quality specifications
- Accurate concentration calculations using peptide content
- Documentation for laboratory records and method sections
- Traceability through batch number reference
- Comparison across experiments using different batches
Accessing COAs
Certificates of Analysis for Peptide Hackers products are available through the COA section of this website. Documents can be viewed online and referenced by batch number.
Browse Certificates of AnalysisLimitations
COAs document material quality at the time of testing. Storage conditions and handling after testing may affect material properties. COAs do not constitute:
- Guarantee of performance in any specific application
- Certification for pharmaceutical or diagnostic use
- Regulatory approval documentation
- Safety data or handling instructions