LL-37
PH-LL37-001
Specifications
Description
LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid sequence with broad-spectrum antimicrobial and immunomodulatory properties.
Mechanism of Action
LL-37 disrupts microbial membranes and modulates immune responses. Research demonstrates antimicrobial activity in platelets (PMID: 36769137) and roles in oral health (PMID: 41544412).
Research Applications
- Antimicrobial peptide research (PMID: 41544412)
- Innate immunity studies (PMID: 36769137)
- Wound healing research
- Immunomodulation studies
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 4493 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- LL-37 oral health review. 2025. PMID: 41544412
- LL-37 platelet antimicrobial activity. 2023. PMID: 36769137
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
LL-37 is a synthetic peptide compound used in laboratory research settings. Researchers studying antimicrobial peptide activity use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for LL-37 — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
