BPC-157
PH-BPC157-001
Specifications
Description
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from human gastric juice proteins. This 15-amino acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has emerged as one of the most extensively studied peptides in tissue repair and regeneration research.
Mechanism of Action
BPC-157 demonstrates pleiotropic beneficial effects primarily mediated through promotion of angiogenesis via enhanced vascular endothelial growth factor (VEGF) expression (Hsieh et al., 2019). The peptide stimulates growth hormone receptor expression, activating signaling pathways essential for cell proliferation and wound healing. Additionally, BPC-157 modulates nitric oxide synthase pathways while inhibiting inflammatory cytokine production (Sikiric et al., 2021).
Research Applications
- Musculoskeletal repair: tendon, ligament, and muscle healing studies demonstrating improved biomechanical strength (Chang et al., 2011)
- Gastrointestinal protection and ulcer management research
- Wound healing and cutaneous regeneration (Gwyer et al., 2019)
- Angiogenesis and vascular development studies
- Neuroprotective research (Seiwerth et al., 2017)
Product Specifications
- Purity: 99.564% (HPLC verified)
- Molecular Weight: 1419.5 Da
- Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Form: Lyophilized powder
- Storage: -20°C
References
- Sikiric P, et al. Curr Pharm Des. 2021. PMID: 33130124
- Hsieh MJ, et al. Front Pharmacol. 2019. PMID: 30652634
- Seiwerth S, et al. World J Gastroenterol. 2017. PMID: 28483263
- Gwyer D, et al. Cell Tissue Res. 2019. PMID: 30915550
- Chang CH, et al. J Appl Physiol. 2011. PMID: 21030672
- Lee E, et al. Altern Ther Health Med. 2021. PMID: 34324435
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
BPC-157 is a synthetic peptide compound used in laboratory research settings. Researchers studying tissue repair and regeneration mechanisms use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for BPC-157 — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
