HMG
PH-HMG-001
Specifications
- Purity (HPLC)
- ≥99%
- Size
- Hmg
- Catalog No.
- PH-HMG-001
Description
HMG (human menopausal gonadotropin) is a preparation with equal activity of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), purified from the urine of postmenopausal women. It's a long-established gonadotropin reference material in reproductive research.
Mechanism
It supplies FSH and LH activity together. FSH drives follicular development and spermatogenesis; LH supports ovulation and Leydig-cell testosterone production. In IVF research, combined FSH/LH activity was associated with fertilization rates comparable or favorable to pure FSH (Westergaard et al., 1996; Gordon & Sauer, 1995).
Research Applications
- Reproductive and assisted-reproduction research (Westergaard et al., 1996)
- HPG-axis studies
- Spermatogenesis and folliculogenesis
- Gonadotropin pharmacology (Gordon & Sauer, 1995)
Product Specifications
- Composition: FSH and LH (1:1 ratio)
- Activity: 75 IU FSH + 75 IU LH per vial
- Form: Lyophilized powder
- Storage: 2-8°C
References
- Westergaard LG, et al. "The effect of human menopausal gonadotrophin and highly purified, urine-derived follicle stimulating hormone on the outcome of in-vitro fertilization." Hum Reprod. 1996. PMID: 8671425
- Gordon CM, Sauer MV. "Generic human menopausal gonadotropin (hMG) in place of more costly follicle-stimulating hormone (FSH) for routine ovulation induction." Fertil Steril. 2001. PMID: 11155320
Sold for laboratory research use only. Not for human or veterinary use.
Verification
Storage & Handling
Storage
HMG is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
HMG is a synthetic peptide compound used in laboratory research settings. Researchers studying peptide biology use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for HMG — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is HMG?
Each lot of HMG is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does HMG include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for HMG documents its purity and identity and is available on our COA page.
How should HMG be stored?
HMG is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is HMG shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can HMG be used on humans or animals?
No. HMG is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.