MK-677
PH-MK677-001
Specifications
Description
MK-677 (Ibutamoren) is an orally active growth hormone secretagogue that mimics ghrelin signaling. This non-peptide compound stimulates sustained GH and IGF-1 elevation.
Mechanism of Action
MK-677 acts as a ghrelin mimetic, activating GHS-R1a receptors to stimulate GH release. Studies demonstrate reversal of diet-induced catabolism (Murphy et al., 1998) and effects on body composition (Falk et al., 2022).
Research Applications
- GH secretagogue studies (Murphy et al., 1998)
- Body composition research (Falk et al., 2022)
- Anti-catabolic effects
- IGF-1 elevation studies
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 528.7 Da
- Form: Powder
- Storage: Room temperature
References
- Murphy MG, et al. J Clin Endocrinol Metab. 1998. PMID: 9467534
- Falk D, et al. J Appl Physiol. 2022. PMID: 36303408
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
MK-677 is a synthetic peptide compound used in laboratory research settings. Researchers studying general research compound applications use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for MK-677 — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
