MK-677
PH-MK677-001
Specifications
- Purity (HPLC)
- ≥99%
- Size
- 10mg
- Molecular Weight
- 528.67 Da
- Catalog No.
- PH-MK677-001
Description
MK-677 (Ibutamoren) is an orally active growth hormone secretagogue that mimics ghrelin signaling. This non-peptide compound stimulates sustained GH and IGF-1 elevation.
Mechanism of Action
MK-677 acts as a ghrelin mimetic, activating GHS-R1a receptors to stimulate GH release. Studies demonstrate reversal of diet-induced catabolism (Murphy et al., 1998) and effects on body composition (Falk et al., 2022).
Research Applications
- GH secretagogue studies (Murphy et al., 1998)
- Body composition research (Falk et al., 2022)
- Anti-catabolic effects
- IGF-1 elevation studies
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 528.7 Da
- Form: Powder
- Storage: Room temperature
References
- Murphy MG, et al. J Clin Endocrinol Metab. 1998. PMID: 9467534
- Falk D, et al. J Appl Physiol. 2022. PMID: 36303408
Verification
Storage & Handling
Storage
MK-677 is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
MK-677 is a synthetic peptide compound used in laboratory research settings. Researchers studying general research compound applications use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for MK-677 — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is MK-677?
Each lot of MK-677 is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does MK-677 include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for MK-677 documents its purity and identity and is available on our COA page.
How should MK-677 be stored?
MK-677 is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is MK-677 shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can MK-677 be used on humans or animals?
No. MK-677 is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
