PT-141 (Bremelanotide)
Catalog no. PH-PT141-001Size 10mgMW (reference) 1,025.2 DaMechanism Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Description
PT-141 (bremelanotide) is a cyclic melanocortin-receptor agonist. It's the research analog in the melanocortin family that's studied mostly for central nervous system signaling rather than peripheral effects.
Mechanism
It activates melanocortin receptors — chiefly MC4R and MC3R — in the central nervous system, a pathway tied to arousal and motivation signaling. Its receptor activity and CNS pharmacology were reviewed by Dhillon & Keam (2019) and Hedlund (2004).
Research Applications
- Melanocortin receptor pharmacology (Hedlund, 2004)
- Central arousal and motivation pathways (Dhillon & Keam, 2019)
- CNS signaling studies
- Structure–activity work on cyclic melanocortin analogs
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 1025.2 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- Dhillon S, Keam SJ. Drugs. 2019. PMID: 31429064
- Hedlund P. Curr Opin Investig Drugs. 2004. PMID: 15134289
Sold for laboratory research use only. Not for human or veterinary use.
SpecsCompound Specifications
Compound Specifications
- Also known as
- PT141, Bremelanotide
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
PT-141 (Bremelanotide) is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
PT-141 (Bremelanotide) is a synthetic peptide compound used in laboratory research settings. Researchers studying melanocortin receptor system research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
PT-141 (Bremelanotide) compound facts
- CAS Number
- 189691-06-3
- Molecular Formula
- C50H68N14O10
- Molecular Weight
- 1,025.2 Da
- Mechanism
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- PubChem CID
- 9941379
- Key PubMed references
- PMID 15134289, PMID 31429064
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is PT-141 (Bremelanotide)?
PT-141 (Bremelanotide) is a research compound supplied for in-vitro laboratory use. Also known as PT141, Bremelanotide. Mechanism class: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Supplied for melanocortin system laboratory research. Research Use Only — not for human or veterinary use.
What purity is PT-141 (Bremelanotide)?
No certificate with an HPLC purity figure is published for PT-141 (Bremelanotide) yet.
Does PT-141 (Bremelanotide) include a Certificate of Analysis?
No certificate is published for PT-141 (Bremelanotide) yet.
How should PT-141 (Bremelanotide) be stored?
PT-141 (Bremelanotide) is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is PT-141 (Bremelanotide) shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can PT-141 (Bremelanotide) be used on humans or animals?
No. PT-141 (Bremelanotide) is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Is PT-141 (Bremelanotide) the same as PT141?
Yes. PT-141 (Bremelanotide) is also spelled or referred to as PT141, Bremelanotide. These are naming variants of the same compound, not different products.
What is the CAS number for PT-141 (Bremelanotide)?
PT-141 (Bremelanotide)'s CAS Registry Number is 189691-06-3, per PubChem (CID 9941379).
What is the price per mg for PT-141 (Bremelanotide)?
The 10mg size of PT-141 (Bremelanotide) is $4.50 per mg. See the size selector above for per-mg pricing on every available size.
