Retatrutide
PH-RETA-001
Specifications
- Purity (HPLC)
- 99.579%
- Size
- 20mg
- Molecular Weight
- ~4700 Da
- Catalog No.
- PH-RETA-001
- Lot
- 2025121210
Description
Retatrutide is a single-molecule triple agonist — it acts on the GIP, GLP-1, and glucagon receptors at once. That three-receptor design is what makes it a compound of interest in metabolic research, since each receptor sits on a different part of glucose and energy handling.
Mechanism
By engaging all three receptors together, retatrutide affects insulin secretion, appetite signaling, and energy expenditure in parallel. Its triple-agonist pharmacology and metabolic profile were characterized by Jastreboff et al. (2023).
Research Applications
- Glucose regulation and energy balance (Jastreboff et al., 2023)
- Obesity and metabolic syndrome models (Abdul-Rahman et al., 2024)
- Incretin and glucagon receptor pharmacology
- Structure–activity work on multi-receptor agonists
Product Specifications
- Purity: 99.579% (HPLC verified)
- Molecular Weight: ~4700 Da
- Form: Lyophilized powder
- Storage: -20°C, protected from light
References
- Jastreboff AM, et al. N Engl J Med. 2023. PMID: 37366315
- Abdul-Rahman T, et al. Diabetes Obes Metab. 2024. PMID: 39515565
Sold for laboratory research use only. Not for human or veterinary use.
Verification
Storage & Handling
Storage
Retatrutide is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
Retatrutide is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Retatrutide — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Retatrutide?
Each lot of Retatrutide is verified to 99.579% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Retatrutide include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Retatrutide documents its purity and identity and is available on our COA page.
How should Retatrutide be stored?
Retatrutide is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Retatrutide shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Retatrutide be used on humans or animals?
No. Retatrutide is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
