Research Peptide

Retatrutide

Retatrutide is a lyophilized powder research compound acting as a triple agonist on GIP, GLP-1, and glucagon receptors. Our current lot, AM20260925-01, tested 99.724% HPLC purity with identity confirmed by Accumark Labs (report CW6X-76R7, completed Sep 28, 2026)

PH-RETA-00199.724%HPLC verified
Lyophilized powder of Retatrutide research compound for metabolic receptor studies
Accumark LabsCertificate of AnalysisReport CW6X-76R7
Lab certificate

Retatrutide certificate of analysis

Lot AM20260925-01

Tested on the 10.467 mg vial

Sample received Sep 24, 2026 · Analysis completed Sep 28, 2026

Retatrutide vial
  • Purity (HPLC)

    • 99.724%

    Conforms spec > 98.0%

  • Identity

    • Retatrutide

    Conforms

  • Quantity

    • 10.467 mg

    Measured

Figures copied exactly from Accumark Labs's report CW6X-76R7.

Catalog no. PH-RETA-001Size 10mgMW (reference) 4,731 DaMechanism GIP/GLP-1/Glucagon triple agonist

Overview

Description

Retatrutide is a lyophilized powder research compound acting as a triple agonist on GIP, GLP-1, and glucagon receptors. It has a purity of 99.724% and a molecular weight of 4,731 Da. This compound is intended for metabolic receptor pharmacology research. Store at -20°C protected from light. For laboratory research use only.

Mechanism of Action

Retatrutide (LY3437943) is a unimolecular triple agonist at GIP, GLP-1, and glucagon receptors. Phase 2 RCT (n=338): -17.5% mean body-weight change at 24 weeks (12 mg group) vs -1.6% placebo; -24.2% at 48 weeks vs -2.1% placebo (Jastreboff et al., 2023).

Research Applications

References

  1. Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — Phase 2 Trial. N Engl J Med. 2023. PMID: 37366315
  2. LY3437943, a novel triple GIP/GLP-1/glucagon receptor agonist — Phase 1b. PMID: 36354040
Specs

Compound Specifications

Also known as
Reta
CAS Number
2381089-83-2
Molecular Formula
C221H342N46O68
Molecular Weight
4,731 Da
Mechanism
GIP/GLP-1/Glucagon triple agonist
PubChem CID
171390338
Form
Lyophilized powder
Storage
−20°C or below, protected from light and moisture
Handling

Storage & Handling

  • Storage

    Retatrutide is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.

  • Stability

    Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.

Research

Research Overview

Retatrutide is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Its available Certificate of Analysis documents the reported laboratory results.

FAQ

Frequently Asked Questions

What is Retatrutide?

Retatrutide is a research compound supplied for in-vitro laboratory use. Also known as Reta. Mechanism class: GIP/GLP-1/Glucagon triple agonist. Supplied for metabolic research laboratory research. A third-party Certificate of Analysis is published for the current lot. Research Use Only — not for human or veterinary use.

What purity is Retatrutide?

The current Certificate of Analysis for Retatrutide reports 99.724% purity by HPLC (Accumark Labs report CW6X-76R7).

Does Retatrutide include a Certificate of Analysis?

Yes. Accumark Labs report CW6X-76R7 for Retatrutide is on our COA page, with a link to the lab's own report.

How should Retatrutide be stored?

Retatrutide is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.

How is Retatrutide shipped?

Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.

Can Retatrutide be used on humans or animals?

No. Retatrutide is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.

Is Retatrutide the same as Reta?

Yes. Retatrutide is also spelled or referred to as Reta. These are naming variants of the same compound, not different products.

What is the CAS number for Retatrutide?

Retatrutide's CAS Registry Number is 2381089-83-2, per PubChem (CID 171390338).

How do I verify the Retatrutide Certificate of Analysis is real?

Open the lab report link on our certificate page — it goes to Accumark Labs's own verification portal, not a file we host, so the result can't be edited by us. Confirm the report ID (CW6X-76R7) and figures match what's shown here.

What is the price per mg for Retatrutide?

The 10mg size of Retatrutide is $9.50 per mg. See the size selector above for per-mg pricing on every available size.

From $95.00$9.50/mg