Adipotide
PH-ADIP-001
Specifications
- Purity (HPLC)
- ≥99%
- Size
- 1mg
- Molecular Weight
- 2465.8 Da
- Catalog No.
- PH-ADIP-001
Description
Adipotide (CKGGRAKDC-GG-D(KLAKLAK)2) is a peptidomimetic that targets the blood supply of white fat. It pairs a homing sequence with a proapoptotic domain so it acts on adipose vasculature specifically.
Mechanism
The CKGGRAKDC sequence binds prohibitin on the vessels feeding white adipose tissue; the attached proapoptotic domain disrupts mitochondrial membranes in those vessels. In obese primate models, that targeted vascular apoptosis reduced adipose mass (Barnhart et al., 2011).
Research Applications
- Adipose vascular targeting (Barnhart et al., 2011)
- Proapoptotic and homing-peptide design
- Prohibitin receptor biology
- Body-composition models in primates
Product Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: -20°C
References
- Barnhart KF, et al. "A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys." Sci Transl Med. 2011. PMID: 22072637
Sold for laboratory research use only. Not for human or veterinary use.
Verification
Storage & Handling
Storage
Adipotide is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
Adipotide is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Adipotide — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Adipotide?
Each lot of Adipotide is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Adipotide include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Adipotide documents its purity and identity and is available on our COA page.
How should Adipotide be stored?
Adipotide is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Adipotide shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Adipotide be used on humans or animals?
No. Adipotide is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
