KLOW
PH-KLOW-001
Specifications
Description
KLOW is a synergistic peptide blend combining four research-backed compounds: KPV, BPC-157, TB-500, and GHK-Cu. This multi-peptide formula targets tissue repair, anti-inflammatory pathways, and skin rejuvenation.
Components & Mechanisms
KPV - A tripeptide derived from α-MSH that inhibits NF-κB activation and reduces pro-inflammatory cytokines. PepT1-mediated KPV uptake reduces intestinal inflammation at nanomolar concentrations (Dalmasso et al., 2008).
BPC-157 - Stable gastric pentadecapeptide that promotes wound healing and angiogenesis. BPC 157 accelerates healing of various tissue wounds including skin, muscle, tendon, and bone (Sikiric et al., 2021).
TB-500 (Thymosin Beta-4) - A multi-functional regenerative peptide that promotes cell migration, angiogenesis, and tissue repair. Thymosin β4 plays a vital role in the repair and regeneration of injured cells and tissues (Goldstein et al., 2012).
GHK-Cu - A copper-binding tripeptide that modulates multiple cellular pathways in skin regeneration, stimulating collagen synthesis and wound healing (Pickart et al., 2015).
Research Applications
- Synergistic tissue repair and wound healing
- Anti-inflammatory mechanism studies
- Skin regeneration and collagen synthesis
- Multi-pathway regenerative research
- Body composition optimization
Product Specifications
- Composition: KPV + BPC-157 + TB-500 + GHK-Cu blend
- Form: Injectable solution
- Storage: 2-8°C
References
- Dalmasso G, et al. "PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation." Gastroenterology. 2008. PMID: 18061177
- Sikiric P, et al. "Stable Gastric Pentadecapeptide BPC 157 and Wound Healing." Curr Pharm Des. 2021. PMID: 34267654
- Goldstein AL, et al. "Thymosin β4: a multi-functional regenerative peptide." Ann N Y Acad Sci. 2012. PMID: 22074294
- Pickart L, et al. "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration." Biomed Res Int. 2015. PMID: 26236730
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
KLOW is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for KLOW — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
