HGH
Catalog no. HGHSize 6 IUMW (reference) Fragment 176-191: 1817.1 Da · Full-length 191-AA (36 IU): ~22,124 DaMechanism Fragment 176-191: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe · 36 IU: full-length 191-amino-acid somatropin (~22.1 kDa)
Description
HGH Fragment 176-191 is the C-terminal piece of human growth hormone (residues 176–191), stabilized for research use. It keeps the lipolytic activity of the parent hormone but, unlike full-length GH, doesn't act on the GH receptor or move blood glucose or IGF-1.
Mechanism
The fragment (also called AOD9604) drives lipolysis in fat tissue, partly by raising beta3-adrenergic receptor expression, without the broader hormonal effects of full GH. In obese-mouse work it increased fat oxidation without engaging the GH receptor or raising blood glucose (Heffernan et al., 2001; Heffernan et al., 2001).
Research Applications
- Selective lipolysis and fat-metabolism studies (Heffernan et al., 2001)
- Adipocyte biology
- Body-composition models without GH-axis effects
- Beta3-adrenergic signaling (Heffernan et al., 2001)
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 1817.1 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- Heffernan MA, et al. "Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment." Int J Obes Relat Metab Disord. 2001. PMID: 11673763
- Heffernan MA, et al. "The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology. 2001. PMID: 11713213
Sold for laboratory research use only. Not for human or veterinary use.
SpecsCompound Specifications
Compound Specifications
- Also known as
- HGH Fragment, Fragment 176-191, 176-191
- Molecular Weight
- Fragment 176-191: 1817.1 Da · Full-length 191-AA (36 IU): ~22,124 Da
- Mechanism
- Fragment 176-191: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe · 36 IU: full-length 191-amino-acid somatropin (~22.1 kDa)
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
HGH is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
HGH is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is HGH?
HGH is a research compound supplied for in-vitro laboratory use. Also known as HGH Fragment, Fragment 176-191, 176-191. Mechanism class: Fragment 176-191: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe · 36 IU: full-length 191-amino-acid somatropin (~22.1 kDa). Supplied for metabolic research laboratory research. Research Use Only — not for human or veterinary use.
What purity is HGH?
No certificate with an HPLC purity figure is published for HGH yet.
Does HGH include a Certificate of Analysis?
No certificate is published for HGH yet.
How should HGH be stored?
HGH is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is HGH shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can HGH be used on humans or animals?
No. HGH is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Is HGH the same as HGH Fragment?
Yes. HGH is also spelled or referred to as HGH Fragment, Fragment 176-191, 176-191. These are naming variants of the same compound, not different products.
