HGH
HGH
Specifications
- Purity (HPLC)
- ≥99%
- Size
- 10 IU
- Molecular Weight
- Fragment 176-191: 1817.1 Da · Full-length 191-AA (36 IU): ~22,124 Da
- Catalog No.
- HGH
Description
HGH Fragment 176-191 is the C-terminal piece of human growth hormone (residues 176–191), stabilized for research use. It keeps the lipolytic activity of the parent hormone but, unlike full-length GH, doesn't act on the GH receptor or move blood glucose or IGF-1.
Mechanism
The fragment (also called AOD9604) drives lipolysis in fat tissue, partly by raising beta3-adrenergic receptor expression, without the broader hormonal effects of full GH. In obese-mouse work it increased fat oxidation without engaging the GH receptor or raising blood glucose (Heffernan et al., 2001; Heffernan et al., 2001).
Research Applications
- Selective lipolysis and fat-metabolism studies (Heffernan et al., 2001)
- Adipocyte biology
- Body-composition models without GH-axis effects
- Beta3-adrenergic signaling (Heffernan et al., 2001)
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 1817.1 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- Heffernan MA, et al. "Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment." Int J Obes Relat Metab Disord. 2001. PMID: 11673763
- Heffernan MA, et al. "The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology. 2001. PMID: 11713213
Sold for laboratory research use only. Not for human or veterinary use.
Verification
Storage & Handling
Storage
HGH is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
HGH is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for HGH — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is HGH?
Each lot of HGH is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does HGH include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for HGH documents its purity and identity and is available on our COA page.
How should HGH be stored?
HGH is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is HGH shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can HGH be used on humans or animals?
No. HGH is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
