Kisspeptin
Catalog no. PH-KISS-001Size 5mgMW (reference) 1,302.4 DaSequence Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Description
Kisspeptin is a family of neuropeptides encoded by the KISS1 gene that serve as critical regulators of reproductive function. These peptides activate the kisspeptin receptor (GPR54/KISS1R) to control gonadotropin-releasing hormone (GnRH) secretion.
Mechanism of Action
Kisspeptin directly stimulates GnRH neurons in the hypothalamus, triggering the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The kisspeptin system is essential for puberty onset and reproductive function, serving as a pivotal factor in the pubertal activation of the reproductive cascade (Kaiser & Kuohung, 2005). Kisspeptin expression in the brain acts as a catalyst for the initiation of puberty (Smith et al., 2007).
Research Applications
- Reproductive endocrinology (Kaiser & Kuohung, 2005)
- Puberty and fertility research (Smith et al., 2007)
- GnRH regulation studies
- Hypogonadism research
- HPG axis modulation
Product Specifications
- Purity: ≥99% (HPLC verified)
- Forms available: Kisspeptin-10, Kisspeptin-54
- Form: Lyophilized powder
- Storage: -20°C
References
- Kaiser UB, Kuohung W. "KiSS-1 and GPR54 as new players in gonadotropin regulation and puberty." Endocrinology. 2005. PMID: 16034182
- Smith JT, et al. "Kisspeptin expression in the brain: catalyst for the initiation of puberty." Trends Endocrinol Metab. 2007. PMID: 17334929
SpecsCompound Specifications
Compound Specifications
- Also known as
- Kisspeptin-10
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
Kisspeptin is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
Kisspeptin is a synthetic peptide compound used in laboratory research settings. Researchers studying neuropeptide signaling and receptor research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Kisspeptin compound facts
- CAS Number
- 374675-21-5
- Molecular Formula
- C63H83N17O14
- Molecular Weight
- 1,302.4 Da
- Sequence
- Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
- PubChem CID
- 25240297
- Key PubMed references
- PMID 16034182, PMID 17334929
Research articles on Kisspeptin
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is Kisspeptin?
Kisspeptin is a research compound supplied for in-vitro laboratory use. Also known as Kisspeptin-10. Sequence: Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2. Supplied for neuropeptides laboratory research. Research Use Only — not for human or veterinary use.
What purity is Kisspeptin?
No certificate with an HPLC purity figure is published for Kisspeptin yet.
Does Kisspeptin include a Certificate of Analysis?
No certificate is published for Kisspeptin yet.
How should Kisspeptin be stored?
Kisspeptin is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is Kisspeptin shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can Kisspeptin be used on humans or animals?
No. Kisspeptin is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Is Kisspeptin the same as Kisspeptin-10?
Yes. Kisspeptin is also spelled or referred to as Kisspeptin-10. These are naming variants of the same compound, not different products.
What is the CAS number for Kisspeptin?
Kisspeptin's CAS Registry Number is 374675-21-5, per PubChem (CID 25240297).
What is the price per mg for Kisspeptin?
The 5mg size of Kisspeptin is $11.00 per mg. See the size selector above for per-mg pricing on every available size.
