Dihexa
Catalog no. PH-DIHEX-001Size 10mgMW (reference) 504.7 DaMechanism Hexanoic-Tyr-Ile-(6) aminohexanoic amide
Description
Dihexa is a small molecule angiotensin IV analog with potent procognitive effects. This orally active compound crosses the blood-brain barrier and acts as an HGF/c-Met system agonist.
Mechanism of Action
Dihexa binds hepatocyte growth factor (HGF) with high affinity and enhances c-Met receptor activation, promoting synaptogenesis and spinogenesis in hippocampal neurons. A systematic review demonstrates consistent cognitive benefits of angiotensin IV analogs including Dihexa in memory and learning tasks (Royea & Bherer, 2018). Research explores therapeutic applications for Alzheimer's and Parkinson's diseases (Wright et al., 2015).
Research Applications
- Cognitive enhancement studies (Royea & Bherer, 2018)
- HGF/c-Met signaling research (Wright et al., 2015)
- Synaptic plasticity and memory formation
- Neurodegenerative disease models
- Neuronal growth factor research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 504.7 Da
- Form: Lyophilized powder
- Storage: -20°C, protected from light
References
- Royea J & Bherer L. J Renin Angiotensin Aldosterone Syst. 2018. PMID: 29733881
- Wright JW, et al. Pharmacol Ther. 2015. PMID: 25455861
SpecsCompound Specifications
Compound Specifications
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
Dihexa is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
Dihexa is a synthetic peptide compound used in laboratory research settings. Researchers studying nootropic mechanisms and cognition-related signaling research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Dihexa compound facts
- CAS Number
- 1401708-83-5
- Molecular Formula
- C27H44N4O5
- Molecular Weight
- 504.7 Da
- Mechanism
- Hexanoic-Tyr-Ile-(6) aminohexanoic amide
- PubChem CID
- 129010512
- Key PubMed references
- PMID 29733881, PMID 25455861
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is Dihexa?
Dihexa is a research compound supplied for in-vitro laboratory use. Mechanism class: Hexanoic-Tyr-Ile-(6) aminohexanoic amide. Supplied for nootropics laboratory research. Research Use Only — not for human or veterinary use.
What purity is Dihexa?
No certificate with an HPLC purity figure is published for Dihexa yet.
Does Dihexa include a Certificate of Analysis?
No certificate is published for Dihexa yet.
How should Dihexa be stored?
Dihexa is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is Dihexa shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can Dihexa be used on humans or animals?
No. Dihexa is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
What is the CAS number for Dihexa?
Dihexa's CAS Registry Number is 1401708-83-5, per PubChem (CID 129010512).
What is the price per mg for Dihexa?
The 10mg size of Dihexa is $8.50 per mg. See the size selector above for per-mg pricing on every available size.
