Semax is a synthetic peptide derived from the ACTH (4-10) fragment with Pro-Gly-Pro extension. Our current lot, AM20260925-12, tested 99.701% HPLC purity with identity confirmed by Accumark Labs (report C8FJ-HB65, completed Oct 1, 2026)
Lot AM20260925-12
Tested on the 9.834 mg vial
Sample received Sep 24, 2026 · Analysis completed Oct 1, 2026
Conforms spec > 98.0%
Conforms
Measured
Figures copied exactly from Accumark Labs's report C8FJ-HB65.
Catalog no. PH-SEMAX-001Size 10mgMW (reference) 813.9 DaSequence Met-Glu-His-Phe-Pro-Gly-Pro
Semax is a synthetic peptide derived from the ACTH (4-10) fragment with Pro-Gly-Pro extension. It has been extensively studied for its nootropic and neuroprotective properties in both animal models and clinical settings.
How Does Semax Work?
Semax activates dopaminergic and serotoninergic brain systems, modulating neurotransmitter levels that influence mood, focus, and cognition (Eremin et al., 2005). Critically, Semax has been shown to increase brain-derived neurotrophic factor (BDNF) expression in the hippocampus and frontal cortex, with effects observable within 20 minutes of administration and persisting for hours (Shadrina et al., 2009; Agapova et al., 2008). Clinical research in stroke rehabilitation demonstrated that Semax administration increased plasma BDNF levels and accelerated functional recovery (Gusev et al., 2018).
What is N-Acetyl Semax Amidate?
N-Acetyl Semax Amidate (NASA) is a modified version of Semax with two key structural changes: an acetyl group added to the N-terminus and an amide group at the C-terminus. These modifications protect the peptide from enzymatic degradation by aminopeptidases and carboxypeptidases, potentially enhancing metabolic stability and bioavailability compared to standard Semax. The same core mechanism—BDNF upregulation and monoaminergic modulation—applies to this enhanced formulation.
Research Applications
References
Semax is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Semax is a synthetic peptide compound used in laboratory research settings. Researchers studying cognitive function and neuroprotection use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Its available Certificate of Analysis documents the reported laboratory results.
Semax is a research compound supplied for in-vitro laboratory use. Sequence: Met-Glu-His-Phe-Pro-Gly-Pro. Supplied for neuropeptides laboratory research. A third-party Certificate of Analysis is published for the current lot. Research Use Only — not for human or veterinary use.
The current Certificate of Analysis for Semax reports 99.701% purity by HPLC (Accumark Labs report C8FJ-HB65).
Yes. Accumark Labs report C8FJ-HB65 for Semax is on our COA page, with a link to the lab's own report.
Semax is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
No. Semax is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Semax's CAS Registry Number is 80714-61-0, per PubChem (CID 9811102).
Open the lab report link on our certificate page — it goes to Accumark Labs's own verification portal, not a file we host, so the result can't be edited by us. Confirm the report ID (C8FJ-HB65) and figures match what's shown here.
The 10mg size of Semax is $5.00 per mg. See the size selector above for per-mg pricing on every available size.
