Epithalon
PH-EPITH-001
Specifications
Description
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural peptide Epithalamin produced by the pineal gland. This peptide has been studied for its effects on telomerase activation and cellular aging.
Mechanism of Action
Epithalon activates telomerase, the enzyme responsible for maintaining telomere length, potentially slowing cellular aging processes (Khavinson et al., 2003). Studies show it promotes overcoming of the division limit in human somatic cells (Khavinson et al., 2004).
Research Applications
- Telomerase activation studies (Khavinson et al., 2003)
- Cellular senescence research (Khavinson et al., 2004)
- Pineal gland function studies
- Lifespan research (PMID: 40141333)
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 390.35 Da
- Sequence: Ala-Glu-Asp-Gly
- Form: Lyophilized powder
- Storage: -20°C, protected from light
References
- Khavinson VKh, et al. Bull Exp Biol Med. 2003. PMID: 12937682
- Khavinson VKh, et al. Bull Exp Biol Med. 2004. PMID: 15455129
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
Epithalon is a synthetic peptide compound used in laboratory research settings. Researchers studying longevity and cellular aging research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Epithalon — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
