Epithalon
PH-EPITH-001
Specifications
- Purity (HPLC)
- ≥99%
- Size
- 10mg
- Molecular Weight
- 390.3 Da
- Catalog No.
- PH-EPITH-001
Description
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural peptide Epithalamin produced by the pineal gland. This peptide has been studied for its effects on telomerase activation and cellular aging.
Mechanism of Action
Epithalon activates telomerase, the enzyme responsible for maintaining telomere length, potentially slowing cellular aging processes (Khavinson et al., 2003). Studies show it promotes overcoming of the division limit in human somatic cells (Khavinson et al., 2004).
Research Applications
- Telomerase activation studies (Khavinson et al., 2003)
- Cellular senescence research (Khavinson et al., 2004)
- Pineal gland function studies
- Lifespan research (PMID: 40141333)
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 390.35 Da
- Sequence: Ala-Glu-Asp-Gly
- Form: Lyophilized powder
- Storage: -20°C, protected from light
References
- Khavinson VKh, et al. Bull Exp Biol Med. 2003. PMID: 12937682
- Khavinson VKh, et al. Bull Exp Biol Med. 2004. PMID: 15455129
Verification
Storage & Handling
Storage
Epithalon is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
Epithalon is a synthetic peptide compound used in laboratory research settings. Researchers studying longevity and cellular aging research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Epithalon — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Epithalon?
Each lot of Epithalon is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Epithalon include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Epithalon documents its purity and identity and is available on our COA page.
How should Epithalon be stored?
Epithalon is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Epithalon shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Epithalon be used on humans or animals?
No. Epithalon is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
