Livagen
Catalog no. PH-LIVA-001Size 20mgMW (reference) 461.5 DaSequence Lys-Glu-Asp-Ala
Description
Livagen (Lys-Glu-Asp-Ala) is a synthetic tetrapeptide bioregulator from the Khavinson short-peptide series.
Mechanism of Action
Livagen (Lys-Glu-Asp-Ala) inhibited enkephalin-degrading enzymes from human serum in vitro (IC50 = 20 μM, more potent than puromycin/leupeptin/D-PAM), with no direct binding observed to mu- or delta-opioid receptors in rat brain membrane fractions (PMID: 12942748). In a separate rat study, oral Livagen produced an age-dependent, bidirectional effect on digestive enzyme activity — decreased in young rats, increased in old rats (PMID: 16075683, in vivo rat).
Research Applications
- Enkephalin-degrading enzyme inhibition, human serum in vitro (PMID: 12942748)
- Age-dependent digestive-enzyme activity across rat tissues, in vivo (PMID: 16075683)
References
- Kost NV, et al. Effect of new peptide bioregulators livagen and epitalon on enkephalin-degrading enzymes in human serum. Izv Akad Nauk Ser Biol. 2003. PMID: 12942748
- Timofeeva NM, et al. Effect of peptide Livagen on activity of digestive enzymes in gastrointestinal tract and non-digestive organs in rats of different ages. Adv Gerontol. 2005. PMID: 16075683
SpecsCompound Specifications
Compound Specifications
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
Livagen is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
Livagen is a synthetic peptide compound used in laboratory research settings. Researchers studying longevity and cellular aging research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Livagen compound facts
- CAS Number
- 433257-50-2
- Molecular Formula
- C18H31N5O9
- Molecular Weight
- 461.5 Da
- Sequence
- Lys-Glu-Asp-Ala
- PubChem CID
- 87919683
- Key PubMed references
- PMID 12942748, PMID 16075683
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is Livagen?
Livagen is a research compound supplied for in-vitro laboratory use. Sequence: Lys-Glu-Asp-Ala. Supplied for longevity research laboratory research. Research Use Only — not for human or veterinary use.
What purity is Livagen?
No certificate with an HPLC purity figure is published for Livagen yet.
Does Livagen include a Certificate of Analysis?
No certificate is published for Livagen yet.
How should Livagen be stored?
Livagen is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is Livagen shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can Livagen be used on humans or animals?
No. Livagen is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
What is the CAS number for Livagen?
Livagen's CAS Registry Number is 433257-50-2, per PubChem (CID 87919683).
What is the price per mg for Livagen?
The 20mg size of Livagen is $3.25 per mg. See the size selector above for per-mg pricing on every available size.
