Research Peptide

IGF-1 LR3

IGF-1 LR3 (Long R3 IGF-1) is a modified form of insulin-like growth factor 1 with enhanced potency and extended half-life. Our current lot, AM20260925-17, tested 99.17% HPLC purity with identity confirmed by Accumark Labs (report 5CA9-GKY9, completed Oct 1, 2026)

PH-IGF1LR3-00199.17%HPLC verified
IGF-1 LR3 research peptide, 99.17% purity
Accumark LabsCertificate of AnalysisReport 5CA9-GKY9
Lab certificate

IGF-1 LR3 certificate of analysis

Lot AM20260925-17

Tested on the 0.078 mg vial

Sample received Sep 24, 2026 · Analysis completed Oct 1, 2026

IGF-1 LR3 vial
  • Purity (HPLC)

    • 99.17%

    Conforms spec > 98.0%

  • Identity

    • IGF-1 LR3

    Conforms

  • Quantity

    • 0.078 mg

    Measured

Figures copied exactly from Accumark Labs's report 5CA9-GKY9.

Catalog no. PH-IGF1LR3-001Size 0.1mgMW (reference) 9111.0 DaSequence 83 amino acid sequence

Overview

Description

IGF-1 LR3 (Long R3 IGF-1) is a modified form of insulin-like growth factor 1 with enhanced potency and extended half-life. The modifications prevent IGF binding protein interactions, increasing bioavailability.

Mechanism of Action

IGF-1 LR3 features a 13-amino acid N-terminal extension and an Arg-to-Glu substitution at position 3, dramatically reducing binding to IGF binding proteins. LR3IGF-I infusion stimulates organ growth while reducing plasma IGF binding protein concentrations (Conlon et al., 1995). This results in prolonged activity and enhanced anabolic effects, with LR3IGF-I capable of supporting cell growth at concentrations at least 200-fold lower than required for insulin (Frenkel et al., 2007).

Research Applications

  • Enhanced IGF-1 signaling studies (Conlon et al., 1995)
  • Cell culture media supplementation (Frenkel et al., 2007)
  • IGF binding protein interactions
  • Muscle growth and regeneration
  • Cell proliferation studies

Product Specifications

  • Purity: ≥99% (HPLC verified)
  • Molecular Weight: 9111 Da
  • Form: Lyophilized powder
  • Storage: -20°C

References

  1. Conlon MA, et al. "Long R3 insulin-like growth factor-I (IGF-I) infusion stimulates organ growth but reduces plasma IGF-I, IGF-II and IGF binding protein concentrations in the guinea pig." J Endocrinol. 1995. PMID: 7561636
  2. Frenkel J, et al. "LONG R3IGF-I as a more potent alternative to insulin in serum-free culture of HEK293 cells." Cytotechnology. 2007. PMID: 17172665
Specs

Compound Specifications

Also known as
IGF1 LR3, IGF-1LR3
Molecular Weight
9111.0 Da
Sequence
83 amino acid sequence
Form
Lyophilized powder
Storage
−20°C or below, protected from light and moisture
Handling

Storage & Handling

  • Storage

    IGF-1 LR3 is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.

  • Stability

    Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.

Research

Research Overview

IGF-1 LR3 is a synthetic peptide compound used in laboratory research settings. Researchers studying growth hormone releasing hormone pathways use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Its available Certificate of Analysis documents the reported laboratory results.

FAQ

Frequently Asked Questions

What is IGF-1 LR3?

IGF-1 LR3 is a research compound supplied for in-vitro laboratory use. Also known as IGF1 LR3, IGF-1LR3. Sequence: 83 amino acid sequence. Supplied for growth hormone releasing laboratory research. A third-party Certificate of Analysis is published for the current lot. Research Use Only — not for human or veterinary use.

What purity is IGF-1 LR3?

The current Certificate of Analysis for IGF-1 LR3 reports 99.17% purity by HPLC (Accumark Labs report 5CA9-GKY9).

Does IGF-1 LR3 include a Certificate of Analysis?

Yes. Accumark Labs report 5CA9-GKY9 for IGF-1 LR3 is on our COA page, with a link to the lab's own report.

How should IGF-1 LR3 be stored?

IGF-1 LR3 is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.

How is IGF-1 LR3 shipped?

Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.

Can IGF-1 LR3 be used on humans or animals?

No. IGF-1 LR3 is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.

Is IGF-1 LR3 the same as IGF1 LR3?

Yes. IGF-1 LR3 is also spelled or referred to as IGF1 LR3, IGF-1LR3. These are naming variants of the same compound, not different products.

How do I verify the IGF-1 LR3 Certificate of Analysis is real?

Open the lab report link on our certificate page — it goes to Accumark Labs's own verification portal, not a file we host, so the result can't be edited by us. Confirm the report ID (5CA9-GKY9) and figures match what's shown here.

What is the price per mg for IGF-1 LR3?

The 0.1mg size of IGF-1 LR3 is $500.00 per mg. See the size selector above for per-mg pricing on every available size.

From $50.00$500.00/mg