MGF
Catalog no. PH-MGF-001Size 10mgMW (reference) 2867.4 DaSequence IGF-1Ec splice variant peptide
Description
MGF (Mechano Growth Factor) is a splice variant of IGF-1 produced locally in muscle tissue in response to mechanical stress. This autocrine growth factor initiates satellite cell activation and muscle hypertrophy.
Mechanism of Action
MGF is expressed in response to mechanical signals and muscle damage, activating quiescent satellite cells to begin the repair process. The MGF-E peptide significantly increases the proliferative life span and delays senescence of satellite cells, enhancing their fusion potential at different ages (Kandalla et al., 2011). MGF is a putative product of IGF-I gene expression involved in tissue repair and regeneration (Goldspink, 2010).
Research Applications
- Muscle repair and regeneration (Kandalla et al., 2011)
- Satellite cell activation (Goldspink, 2010)
- IGF-1 splice variant research
- Mechanical signaling pathways
- Sarcopenia and muscle aging
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: ~2800 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- Kandalla PK, et al. "Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages." Mech Ageing Dev. 2011. PMID: 21354439
- Goldspink G. "Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration." Endocrinology. 2010. PMID: 20130113
SpecsCompound Specifications
Compound Specifications
- Also known as
- Mechano Growth Factor
- Molecular Weight
- 2867.4 Da
- Sequence
- IGF-1Ec splice variant peptide
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
MGF is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
MGF is a synthetic peptide compound used in laboratory research settings. Researchers studying growth hormone releasing hormone pathways use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is MGF?
MGF is a research compound supplied for in-vitro laboratory use. Also known as Mechano Growth Factor. Sequence: IGF-1Ec splice variant peptide. Supplied for growth hormone releasing laboratory research. Research Use Only — not for human or veterinary use.
What purity is MGF?
No certificate with an HPLC purity figure is published for MGF yet.
Does MGF include a Certificate of Analysis?
No certificate is published for MGF yet.
How should MGF be stored?
MGF is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is MGF shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can MGF be used on humans or animals?
No. MGF is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Is MGF the same as Mechano Growth Factor?
Yes. MGF is also spelled or referred to as Mechano Growth Factor. These are naming variants of the same compound, not different products.
What is the price per mg for MGF?
The 10mg size of MGF is $16.00 per mg. See the size selector above for per-mg pricing on every available size.
