Mod GRF 1-29
Catalog no. PH-MODGRF-001Size 10mgMW (reference) 3367.9 DaMechanism Modified GHRH(1-29)
Description
Mod GRF 1-29 (Modified GRF, CJC-1295 no DAC) is a modified analog of the first 29 amino acids of growth hormone-releasing hormone with enhanced stability. This tetrasubstituted peptide resists enzymatic degradation.
Mechanism of Action
Mod GRF 1-29 features four amino acid substitutions (positions 2, 8, 15, and 27) that protect against DPP-IV cleavage while maintaining GHRH receptor binding. These modifications extend half-life while preserving pituitary GH-releasing activity (Jette et al., 2005). GHRH-(1-29) administered twice daily reverses the decreased GH and IGF-I levels in elderly men (Corpas et al., 1992).
Research Applications
- Stabilized GHRH analog research (Jette et al., 2005)
- Pulsatile GH release studies (Corpas et al., 1992)
- Combined GHRH/GHRP synergy
- GH axis modulation
- Peptide stability research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 3367.9 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- Jette L, et al. "Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog." Endocrinology. 2005. PMID: 15817669
- Corpas E, et al. "Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men." J Clin Endocrinol Metab. 1992. PMID: 1379256
SpecsCompound Specifications
Compound Specifications
- Also known as
- Modified GRF 1-29, ModGRF
- Molecular Weight
- 3367.9 Da
- Mechanism
- Modified GHRH(1-29)
- Form
- Lyophilized powder
- Storage
- −20°C or below, protected from light and moisture
HandlingStorage & Handling
Storage & Handling
Storage
Mod GRF 1-29 is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
ResearchResearch Overview
Research Overview
Mod GRF 1-29 is a synthetic peptide compound used in laboratory research settings. Researchers studying growth hormone releasing hormone pathways use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. No third-party certificate is on file for this product yet.
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What is Mod GRF 1-29?
Mod GRF 1-29 is a research compound supplied for in-vitro laboratory use. Also known as Modified GRF 1-29, ModGRF. Mechanism class: Modified GHRH(1-29). Supplied for growth hormone releasing laboratory research. Research Use Only — not for human or veterinary use.
What purity is Mod GRF 1-29?
No certificate with an HPLC purity figure is published for Mod GRF 1-29 yet.
Does Mod GRF 1-29 include a Certificate of Analysis?
No certificate is published for Mod GRF 1-29 yet.
How should Mod GRF 1-29 be stored?
Mod GRF 1-29 is supplied as a lyophilized powder. Store it at −20°C or below, protected from light and moisture — lyophilized material is stable frozen. Once reconstituted, keep it refrigerated and avoid freeze-thaw cycles.
How is Mod GRF 1-29 shipped?
Orders ship at a $15 flat rate, free on orders of $200 or more, in discreet, insulated packaging. Domestic delivery takes 2–3 business days — 2-day across California, nearby Nevada, and on orders of $250+.
Can Mod GRF 1-29 be used on humans or animals?
No. Mod GRF 1-29 is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
Is Mod GRF 1-29 the same as Modified GRF 1-29?
Yes. Mod GRF 1-29 is also spelled or referred to as Modified GRF 1-29, ModGRF. These are naming variants of the same compound, not different products.
What is the price per mg for Mod GRF 1-29?
The 10mg size of Mod GRF 1-29 is $7.00 per mg. See the size selector above for per-mg pricing on every available size.
