L-Carnitine
PH-LCAR-001
Specifications
Description
L-Carnitine is a naturally occurring amino acid derivative essential for fatty acid transport into mitochondria for energy production. This quaternary ammonium compound plays a critical role in cellular metabolism.
Mechanism of Action
L-Carnitine shuttles long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation, enhancing energy production from lipids. L-Carnitine is one of the key nutrients for proper mitochondrial function and plays a major part in protecting cellular membranes, preventing fatty acid accumulation, and modulating ketogenesis (Virmani & Cirulli, 2022). Significant increases in mitochondrial function were observed in human neuronal cells exposed to L-carnitine (Ferreira & McKenna, 2013).
Research Applications
- Fatty acid metabolism and energy production (Virmani & Cirulli, 2022)
- Mitochondrial function in neuronal cells (Ferreira & McKenna, 2013)
- Exercise performance
- Cognitive function in aging
- Cardiovascular health research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 161.2 Da
- Form: White crystalline powder
- Storage: Room temperature
References
- Virmani MA, Cirulli M. "The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation." Int J Mol Sci. 2022. PMID: 35269860
- Ferreira GC, McKenna MC. "L-carnitine exposure and mitochondrial function in human neuronal cells." Neurochem Int. 2013. PMID: 24005823
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
L-Carnitine is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for L-Carnitine — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
