Semaglutide
PH-SEMA-001
Specifications
- Purity (HPLC)
- 99.982%
- Size
- 10mg
- Molecular Weight
- 4113.6 Da
- Catalog No.
- PH-SEMA-001
- Lot
- 7832
Description
Semaglutide is a long-acting GLP-1 receptor analog. A few structural changes give it an extended half-life, which is why it's used widely as a GLP-1 reference compound in metabolic research.
Mechanism
It binds the GLP-1 receptor, which drives glucose-dependent insulin release and lowers glucagon output, and it also acts on appetite-related signaling. Its receptor pharmacology and metabolic effects were examined by Rubino et al. (2021) and Chao et al. (2021).
Research Applications
- GLP-1 receptor pharmacology (Chao et al., 2021)
- Energy balance and body-composition models (Rubino et al., 2021)
- Glucose regulation studies
- Metabolic syndrome models
Product Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: -20°C
References
- Rubino D, et al. JAMA. 2021. PMID: 33755728
- Chao AM, et al. Obesity. 2021. PMID: 34706925
Sold for laboratory research use only. Not for human or veterinary use.
Verification
Storage & Handling
Storage
Semaglutide is supplied as a lyophilized powder. Keep it sealed, dry, and away from light until reconstitution.
Reconstitution
Let the vial reach room temperature before opening, then add solvent slowly down the vial wall — do not shake.
Stability
Lyophilized material is stable when frozen. Once reconstituted, keep it cold and minimise handling to preserve integrity.
Research Overview
Semaglutide is a synthetic peptide compound used in laboratory research settings. Researchers studying metabolic regulation and energy homeostasis use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Semaglutide — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Semaglutide?
Each lot of Semaglutide is verified to 99.982% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Semaglutide include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Semaglutide documents its purity and identity and is available on our COA page.
How should Semaglutide be stored?
Semaglutide is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Semaglutide shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Semaglutide be used on humans or animals?
No. Semaglutide is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
